Welcome to TransPan
Identification of biological markers for prevention and translational medicine in pancreatic cancer
Pancreatic cancer (PC) has a high mortality rate and is projected to become a massive public health problem in Europe. The TRANSPAN COST action aims to boost research on the prevention of PC, particularly in the discovery of genetic risk factors, risk stratification, identification of biomarkers for early detection and patient monitoring, elucidation of biological mechanisms and functional pharmacogenomics for personalised medicine.


COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation

These aims will be attained by expanding an existing interdisciplinary network and organised in four working groups
Working Group 1 - Disease Risk Profiling
This WG will use germline genetic variants, epigenetics, transcriptomics and environmental factors to model disease risk and apply risk stratification scores to better select individuals eligible to be screened for PC or its precursors.
Working Group 2 - Non-Invasive Biomarkers
This WG will apply state-of-the-art liquid biopsies for the detection and characterization of circulating tumor cells and DNA, tumor-derived exosomes, tumor-educated platelets, epigenetic markers, and will test their diagnostic value for PC precursors and early-stage PC.
Working Group 3 - Tumor Profiling
Genomic, epigenomic and transcriptional profiling of PC and its precursors in a multiregional analysis fashion will be used to identify novel biomarkers with prognosis and predictive value for PC patient stratification.
Working Group 4 - Functional genomics and therapy
This WG will functionally validate candidate genetic variants from germline or tumor studies by using cutting-edge approaches such as CRISPR-Cas9 gene editing. It will also generate novel approaches such as organoids / zebrafish avatars to implement (chemo)therapeutic strategies based on the patient in an effort to implement personalized medicine for PC.
Latest Events

TRANSPAN Early Career Investigator’s Meeting
TRANSPAN Early Career Investigator’s Meeting
Latest News

Early Career Investigators’ Meeting pre-announcement
This workshop is specifically designed for early career researchers. It is dedicated to PhD...


Transpan at EPC – Santiago de Compostela, Spain, 28th of June
During the 56th EPC conference Transpan benefited from a dedicated session where the early career...

The Second General Meeting of Transpan – Santiago de Compostela, Spain, 24th-25th of June 2024
During the second General Meeting, we reported on the previous activities within the Action and...
Latest Action Calls
This is a collection of all our calls about Open PhD and Post-Doc Positions, Short-Term Scientific Missions, Training Schools and other Grant Opportunities
TRANSPAN Short-Term Scientific Mission (STSM) Opportunities - 2025
STSM Opportunity at Biomedical Research Center, Slovak Academy of Sciences (Slovakia)
Host PI: Bozena Smolkova
Department: Molecular Oncology
Project: DNA methylation analysis by pyrosequencing (DNA methylation quantification in circulating cfDNA)
Number of visitors that can be hosted simultaneously: 2
Accessibility period: February 1 – June 30, 2025
Duration: Minimum 7 days, Maximum 30 days
Living costs: Not specified
Description: This STSM provides an opportunity to work on DNA methylation analysis in circulating cfDNA, gaining experience in pyrosequencing techniques. Ideal for researchers interested in epigenetic modifications in cancer and other diseases.
STSM Opportunity at University College London (UK)
Host PI: Professor Nguyen TK Thanh, MAE FRSC FInstP FAPS
Department: UCL Healthcare Biomagnetics and Nanomaterials Laboratory
Project: Diagnosis of cancer using small iron oxide nanoparticles for MRI contrast enhancement and targeted therapy
Number of visitors that can be hosted simultaneously: 4
Accessibility period: February 1 – September 30, 2025
Duration: Minimum 7 days, Maximum 30 days
Living costs: Approx. £120 per day for a hotel
Description: This STSM provides an opportunity to work with leading experts in nanomedicine, focusing on the use of iron oxide nanoparticles for cancer imaging and therapy. Ideal for researchers in chemistry, biochemistry, and biomedical sciences.
STSM Opportunity at University of Bari "Aldo Moro" (Italy)
Host PI: Mauro Cives
Department: Interdisciplinary Department of Medicine
Project: Two available projects focused on (1) translational research in neuroendocrine tumors and (2) clinical genomics and molecular oncology
Number of visitors that can be hosted simultaneously: 2
Accessibility period: March 1 – September 30, 2025
Duration: Minimum 60 days, Maximum 180 days
Living costs: Between €1,000 and €1,500 per month
Description: This STSM offers hands-on experience in translational and clinical genomic research, focusing on neuroendocrine tumors. Researchers will have the opportunity to work with patient-derived data and explore the molecular basis of these cancers.
STSM Opportunity at University of Coimbra (Portugal)
Host PI: Joel Perdiz Arrais
Department: DEI/ CISUC
Project: AI-driven approaches for cancer diagnosis and precision medicine
Number of visitors that can be hosted simultaneously: 1
Accessibility period: March 1 – September 30, 2025
Duration: Minimum 6 days, Maximum 30 days
Living costs: Approx. €50 per day
Description: This STSM is ideal for researchers interested in AI applications in oncology. The project focuses on developing and implementing AI-driven tools for cancer diagnosis and personalized treatment strategies.
Call for Short-Term Scientific Mission (STSM) Applications - 2025
The COST Action CA21116 “Identification of biological markers for prevention and translational medicine in pancreatic cancer (TRANSPAN)” opens a call for applications for Short-Term Scientific Missions (STSMs) to be developed under the scope of the referred Action, in the terms described in this document.
The main procedures/regulations concerning STSMs can be found here:
Annotated-Rules V2.0 (see A2-1.1 MOBILITY OF RESEARCHERS AND INNOVATORS)
COST Open Call – Proposers’ Guidelines
Contents
1. Scope of TRANSPAN COST Action
2. Purpose of STSMs
3. Eligibility criteria
4. Application deadlines
5. Funding
6. Application procedure
7. Intellectual Property Rights concerns
8. Selection committee
9. Evaluation criteria and communication of the results
10. STSM reporting and payment
11. STSM contacts
Links
1. Scope of TRANSPAN COST Action
For details and specific objectives, please read the Memorandum of Understanding (MoU).
2. Purpose of STSMs
STSMs are stays of a researcher or innovator to a host organization located in a different country than the country of affiliation (for Affiliation, see Article 4.1.1.1.1 on Annotated Rules for COST Actions document) for a specific work and for a determined period.
An STSM should specifically contribute to the scientific objectives of the COST Action, helping to achieve the Action MoU objectives and deliverables.
3. Eligibility criteria
a. The Grant applicant(s) are Action participants with a primary affiliation to a legal entity located in a COST Full or Cooperating Member country, a COST Near Neighbour Country or a European Research and Innovation Organization (see Article 4.1.1.1.1 on Annotated Rules for COST Actions).
b. The Grant applicant is a researcher or innovator who visits a host organization located in a different country than the country of affiliation for a specific work and for a determined period of time.
c. The STSM must have a minimum duration of 5 calendar days (including travel) and end by June 30th, 2025.
d. The COST Association and the Grant Holder of the Action cannot be considered as being an STSM grantee’s employer, i.e., the STSM Grant cannot be considered as a salary.
4. Application deadlines
Application Deadlines Applications will be evaluated continuously as they are received. A second call may be issued mid-year, depending on the availability of remaining funds.
Only applications submitted correctly and at least three weeks before the start of the STSM will be evaluated.
To ensure the optimal use of resources allocated to STSMs, priority will be given to applications for missions starting by 30 June 2025. A second call will open in spring 2025 for missions scheduled between June and September 2025.
5. Funding
In compliance with the Annotated rules the maximum amount that can be reimbursed is 4,000€. However, under this call the maximum amount that may be granted to each applicant will be evaluated before approval by the TRANSPAN Core Group. If the requested budget is not approved, the proponent may be asked to submit a new application with a reduced budget.
An STSM Grant is a lump financial contribution. Please note that STSM Grants do not necessarily cover all expenses related to undertaking a given mission, being only a contribution to the overall travel, accommodation and meal expenses of the Grantee.
The TRANSPAN Core Group recommends using the following guideline to estimate if your budget request falls within an acceptable range:
- Multiply the number of days of the STSM by 50% of the COST daily allowance of the country you where your host lab is located. COST daily allowances are found here: https://www.cost.eu/uploads/2024/11/2024-Daily-allowance-table.pdf;
- Add 500€ for travel;
- Round up to the nearest hundred euros.
If the total exceeds 4000€, your budget request will be 4000€ (this is the maximum allowed by COST for STSMs).
This formula serves as a maximum budget calculation tool and is not binding; applicants may adjust allocations as needed, provided the total request does not exceed the calculated maximum. For example, travel expenses do not need to be capped at 500€. If properly justified, a higher expense is permissible.
STSM grantees should make their own arrangements for all provisions related to personal security, health, taxation, social security and pension matters.
The Grant Holder Institution pays grants after the completion of the activity and approval of all required report/documentation. However, STSMs grantees may request up to 50% pre-payment of the approved grant. This amount is subject to availability of funds and approval by the Grant Holder Institution. The request of pre-payment shall be submitted to the Grant
Awarding Coordinator (manuel.gentiluomo@unipi.it) and the Grant Holder Manager (mailto:a.nelson@dkfz.de).
To be considered concluded, an STSM will require, in addition to the mandatory documentation imposed by the COST rules (section A2-2.3), a letter signed by the host scientist to be sent within one week of the end date set for the grant.
6. Application procedure
The application procedure is legally bound to the Rules for COST Actions. Eligible STSM applicants must submit their STSM applications online by logging into e-COST (https://e-services.cost.eu) and go to “Grant applications” and click on “Apply for a grant”.
The applicant can select “Continue” on the “Short-Term Scientific Mission grant” section.
The application form will contain different sections, some are pre-filled by e-COST, such as Application name or Primary affiliation.
After completing the Grant application form by filling all above-mentioned sections, the applicant also needs to upload:
I. the Grant Application Template (you can find it here: https://www.cost.eu/STSM_GrantApplication).
II. Acceptance/Invitation letter from the host institution: it is the responsibility of the applicant to obtain a written agreement from the host institution stating that the applicant will perform the activities detailed in the STSM working plan on the agreed dates. The letter must be dated back not more than 3 months and must be signed by a permanent staff representative of the host institution (e.g., head of the research group, PI, director of the department, head of the institute/division etc.).
III. Candidate CV: a short (max. 2 pages) CV should be submitted, including academic publications.
In the Application template please briefly address the following points:
a. **Proposed contribution to the scientific objectives of the Action:** Projects not clearly aligned with TRANSPAN's objectives will be rejected outright.
b. Detail which techniques or equipment you plan to use, if applicable.
c. Underline the aspects of complementarity between expertise and instrumentation of the home and hosting institution/research groups.
d. Detail the steps you will take to achieve your proposed goals.
e. Provide an itemized justification of the requested budget.
Applicants are requested to present a working plan that is reasonably feasible and coherent with the time slot requested in the application.
After adding the supporting documents, the applicant can submit the grant application.
Non-compliance with the above listed points will result in exclusion from the proposal evaluation.
PROPOSALS THAT DO NOT CLEARLY DEMONSTRATE A DIRECT AND RELEVANT CONNECTION TO THE OBJECTIVES OF TRANSPAN WILL BE REJECTED WITHOUT APPEAL.
7. Intellectual Property Rights concerns
In case of potential intellectual property concern requested by the host and/or sending institutions, this must be mentioned in the application and managed by IP teams from host and/or sending institutions. In this case, the reviewers of the application may be requested to sign a confidential agreement.
8. Selection committee
The selection of applicants is based on the scientific scope of the STSM application, which must be coherent with the overall objectives of the Action. The STSM evaluation and selection will be carried out by TRANSPAN Core Group.
9. Evaluation criteria and communication of the results
The general criteria for the evaluation of STSM proposals are:
- Clarity of activity planning (working plan) and complementarity of resources between home and host institutions/research groups (resources are intended as: technical expertise, infrastructure, or instrumentation).
- Main expected results and their contribution to the progress towards the Action objectives and deliverables.
- Priority to applicants from inclusiveness target countries (ITCs).
- Curriculum Vitae (CV) of the applicant. In line with the vision of the TRANSPAN action, networking activities such as STSMs will primarily target young researchers and future scientists. Therefore, tenured-track researchers, principal investigators (PIs), professors, and established professionals will not be eligible for STSMs.
Applicants will receive a response within two weeks of submission.
The Grant Holder will inform each approved applicant by sending a Grant Letter generated from e-COST. The applicant must return this letter of acceptance with his/her signature.
10. STSM reporting and payment
Within 30 days from the end date of the STSM (or 15 days after the end of the Grant Period, whichever date comes first), the successful applicant must submit (A) the scientific report, (B) the dissemination materials and (C) the approval letter of the scientific report from the Host institution. These documents must be uploaded on e-COST to proceed with the request for payment.
A) Scientific reports on e-COST:
- A template for the report can be found in e-COST (https://www.cost.eu/STSM_Report) (max 4 pages).
When preparing the scientific report please consider the following:
- The scientific report for COST is a public document. Please take this into account in terms of Intellectual Property Rights.
- The scientific report does not need to contain specific and detailed results of the research. Rather, it should focus on the aspects that are the aim of STSM, in particular how the collaborative research during STSM has strengthened the scientific relationship between Home and Hosting institutions within the framework of COST.
A copy of the scientific report in PDF format must be sent, by email, to the Grant Awarding Coordinator.
The Grant Awarding Coordinator will be responsible for approving the scientific report and informing the Action Chair and the Grant Holder that the STSM has been successfully accomplished.
(Please note that the COST Association can request additional information to substantiate the information contained within the documents submitted by STSM applicants).
B) Dissemination materials to Science Communication Team (stfnbndc@gmail.com):
- A poster/short video/success story describing the subject of your collaborative STSM activities.
- A short advertising sentence summarizing your STSM experience that will be used for promotion of the above material.
- Your credentials in social media (if available) to tag you in the publication of your post.
Please remember to present home and host institutions and your passion for science. Use pictures showing you at work but also after-work. Do not sound too abstract, avoid scientific jargon, use short sentences. The material is to advertise TRANSPAN research, promote you, and will be shown in social media for a public audience.
The materials have to be sent directly to the Science Communication Manager.
C) Host approval of scientific report:
An official letter from the host scientist (affiliated with the host institution), formally confirming the acceptance of the scientific report and verifying the proper execution of the STSM according to the approved plan. Failure to submit the scientific report and dissemination materials and host approval of the report within the above specified timeframe will effectively cancel the Grant. The grantee shall be aware that the COST Association reserves the right to postpone or cancel all payments and to recover the amounts paid to the grantee in case the grantee does not fulfil their obligations.
All STSM grantees are required to give an oral presentation during the TRANSPAN general assembly or a webinar, where they must present the main points of their activity and/or the results they obtained during their STSM.
11. STSM contacts
Dr. Manuel Gentiluomo
CA21116 Grant Awarding Coordinator
Department of Biology
University of Pisa
manuel.gentiluomo@unipi.it
Links
Annotated Rules for COST Actions
(https://www.cost.eu/uploads/2024/11/COST-094-21-V2.0-Annotated-Rules-for-COST-Actions-Level-C.pdf)
Grant Awarding User Guide
(https://www.cost.eu/uploads/2021/12/Grant-Awarding-userguide.pdf)